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1

Chronic Renal Disease || Pathophysiology of Proteinuria: Albuminuria as a Target for Treatment

Heerspink, Hiddo J.L.

Year:

2020

Language:

english

File:

PDF, 1.57 MB

english, 2020

2

Effect of SGLT2 inhibitors on cardiovascular, renal and safety outcomes in patients with type 2 diabetes mellitus and chronic kidney disease: a systematic review and meta-analysis

Toyama, Tadashi, Neuen, Brendon L., Jun, Min, Ohkuma, Toshiaki, Neal, Bruce, Jardine, Meg, Heerspink, Hiddo L., Wong, Muh Geot, Ninomiya, Toshiharu, Wada, Takashi, Perkovic, Vlado

Journal:

Diabetes, Obesity and Metabolism

Year:

2019

Language:

english

File:

PDF, 2.43 MB

english, 2019

3

SGLT2 inhibitors for the prevention of kidney failure in patients with type 2 diabetes: a systematic review and meta-analysis

Neuen, Brendon L, Young, Tamara, Heerspink, Hiddo J L, Neal, Bruce, Perkovic, Vlado, Billot, Laurent, Mahaffey, Kenneth W, Charytan, David M, Wheeler, David C, Arnott, Clare, Bompoint, Severine, Levin

Journal:

The Lancet Diabetes & Endocrinology

Year:

2019

Language:

english

File:

PDF, 1.59 MB

english, 2019

4

Machine Learning based Early Prediction of Endâstage Renal Disease in Patients with Diabetic Kidney Disease using Clinical Trials Data

Belur Nagaraj, Sunil, Pena, Michelle J, Ju, Wenjun, Heerspink, Hiddo L

Journal:

Diabetes, Obesity and Metabolism

Year:

2020

File:

PDF, 1.60 MB

2020

5

Clinical and radiological outcome of conservative vs. surgical treatment of atraumatic degenerative rotator cuff rupture: design of a randomized controlled trial

Frederik O Lambers Heerspink, Roy AG Hoogeslag, Ron L Diercks, Pepijn JM van Eerden, Inge van den Akker-Scheek, Jos JAM van Raay

Journal:

BMC Musculoskeletal Disorders

Year:

2011

Language:

english

File:

PDF, 239 KB

english, 2011

6

Relative Incidence of ESRD Versus Cardiovascular Mortality in Proteinuric Type 2 Diabetes and Nephropathy: Results From the DIAMETRIC (Diabetes Mellitus Treatment for Renal Insufficiency Consortium) Database

David K. Packham, Tahira P. Alves, Jamie P. Dwyer, Robert Atkins, Dick de Zeeuw, Mark Cooper, Shahnaz Shahinfar, Julia B. Lewis, Hiddo J. Lambers Heerspink

Journal:

American Journal of Kidney Diseases

Year:

2012

Language:

english

File:

PDF, 622 KB

english, 2012

7

Comparing surgical repair with conservative treatment for degenerative rotator cuff tears: a randomized controlled trial

Lambers Heerspink, Frederik O., van Raay, Jos J.A.M., Koorevaar, Rinco C.T., van Eerden, Pepijn J.M., Westerbeek, Robin E., van 't Riet, Esther, van den Akker-Scheek, Inge, Diercks, Ronald L.

Journal:

Journal of Shoulder and Elbow Surgery

Year:

2015

Language:

english

File:

PDF, 403 KB

english, 2015

8

Predictors of Atrasentan-Associated Fluid Retention and Change in Albuminuria in Patients with Diabetic Nephropathy

Kohan, D. E., Lambers Heerspink, H. J., Coll, B., Andress, D., Brennan, J. J., Kitzman, D. W., Correa-Rotter, R., Makino, H., Perkovic, V., Hou, F. F., Remuzzi, G., Tobe, S. W., Toto, R., Parving, H.-

Journal:

Clinical Journal of the American Society of Nephrology

Year:

2015

Language:

english

File:

PDF, 652 KB

english, 2015

9

Glomerular Hyperfiltration in Diabetes: Mechanisms, Clinical Significance, and Treatment

Tonneijck, Lennart, Muskiet, Marcel H.A., Smits, Mark M., van Bommel, Erik J., Heerspink, Hiddo J.L., van Raalte, Daniël H., Joles, Jaap A.

Journal:

Journal of the American Society of Nephrology

Year:

2017

Language:

english

File:

PDF, 1.26 MB

english, 2017

10

Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy

Levin, Adeera, Tonelli, Marcello, Bonventre, Joseph, Coresh, Josef, Donner, Jo-Ann, Fogo, Agnes B, Fox, Caroline S, Gansevoort, Ron T, Heerspink, Hiddo J L, Jardine, Meg, Kasiske, Bertram, Köttgen, An

Journal:

Year:

2017

Language:

english

File:

PDF, 950 KB

english, 2017

11

Rationale and protocol of the Study of Diabetic Nephropathy with Atrasentan (SONAR) trial: A clinical trial design novel to diabetic nephropathy

Heerspink, Hiddo J.L., Andress, Dennis L., Bakris, George, Brennan, John J., Correa-Rotter, Ricardo, Dey, Jyotirmoy, Hou, Fan-Fan, Kitzman, Dalane W., Kohan, Donald, Makino, Hirofumi, McMurray, John,

Journal:

Diabetes, Obesity and Metabolism

Year:

2018

Language:

english

File:

PDF, 1.09 MB

english, 2018

12

ACCORDION: Ensuring That We Hear the Music Clearly

Wong, Muh Geot, Heerspink, Hiddo J.L., Perkovic, Vlado

Journal:

Clinical Journal of the American Society of Nephrology

Year:

2018

Language:

english

File:

PDF, 490 KB

english, 2018

13

New pharmacological strategies for protecting kidney function in type 2 diabetes

Muskiet, Marcel H A, Wheeler, David C, Heerspink, Hiddo J L

Journal:

The Lancet Diabetes & Endocrinology

Year:

2018

Language:

english

File:

PDF, 308 KB

english, 2018

14

Change in albuminuria as a surrogate endpoint for progression of kidney disease: a meta-analysis of treatment effects in randomised clinical trials

Heerspink, Hiddo J L, Greene, Tom, Tighiouart, Hocine, Gansevoort, Ron T, Coresh, Josef, Simon, Andrew L, Chan, Tak Mao, Hou, Fan Fan, Lewis, Julia B, Locatelli, Francesco, Praga, Manuel, Schena, Fran

Journal:

The Lancet Diabetes & Endocrinology

Year:

2019

Language:

english

File:

PDF, 894 KB

english, 2019

15

Predicting individual treatment response in diabetes

Heerspink, Hiddo J L

Journal:

The Lancet Diabetes & Endocrinology

Year:

2019

Language:

english

File:

PDF, 117 KB

english, 2019

16

Kidney outcomes associated with use of SGLT2 inhibitors in real-world clinical practice (CVD-REAL 3): a multinational observational cohort study

Heerspink, Hiddo J L, Karasik, Avraham, Thuresson, Marcus, Melzer-Cohen, Cheli, Chodick, Gabriel, Khunti, Kamlesh, Wilding, John P H, Garcia Rodriguez, Luis Alberto, Cea-Soriano, Lucia, Kohsaka, Shun,

Journal:

The Lancet Diabetes & Endocrinology

Year:

2020

File:

PDF, 661 KB

2020

17

Renal outcomes of SGLT2 inhibitors and GLP1 agonists in clinical practice

van der Aart-van der Beek, Annemarie B., Heerspink, Hiddo J. L.

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2020

File:

PDF, 652 KB

2020

18

Surgical repair versus conservative treatment and subacromial decompression for the treatment of rotator cuff tears

Schemitsch, C., Chahal, J., Vicente, M., Nowak, L., Flurin, P-H., Lambers Heerspink, F., Henry, P., Nauth, A.

Journal:

The Bone & Joint Journal

Year:

2019

File:

PDF, 615 KB

2019

19

Extensive Achilles tendon ossification: Repair using a fascia lata graft

Gendera, H.A.M., Lambers-Heerspink, F.O., Bruls, V.E., Drees, M.M.W.

Journal:

Year:

2020

File:

PDF, 2.98 MB

2020

20

SGLT2 Inhibition for CKD and Cardiovascular Disease in Type 2 Diabetes: Report of a Scientific Workshop Sponsored by the National Kidney Foundation

Tuttle, Katherine R., Brosius, Frank C., Cavender, Matthew A., Fioretto, Paola, Fowler, Kevin J., Heerspink, Hiddo J.L., Manley, Tom, McGuire, Darren K., Molitch, Mark E., Mottl, Amy K., Perreault, Le

Journal:

Year:

2020

File:

PDF, 1.76 MB

2020

21

SGLT2 Inhibition for CKD and Cardiovascular Disease in Type 2 Diabetes: Report of a Scientific Workshop Sponsored by the National Kidney Foundation

Tuttle, Katherine R., Brosius, Frank C., Cavender, Matthew A., Fioretto, Paola, Fowler, Kevin J., Heerspink, Hiddo J.L., Manley, Tom, McGuire, Darren K., Molitch, Mark E., Mottl, Amy K., Perreault, Le

Journal:

American Journal of Kidney Diseases

Year:

2020

File:

PDF, 318 KB

2020

22

Sulodexide for Kidney Protection in Type 2 Diabetes Patients With Microalbuminuria: A Randomized Controlled Trial

Edmund J. Lewis, Julia B. Lewis, Tom Greene, Lawrence G. Hunsicker, Tomas Berl, Marc A. Pohl, Dick de Zeeuw, Hiddo Lambers Heerspink, Richard D. Rohde, Robert C. Atkins, Anne T. Reutens, David K. Pack

Journal:

American Journal of Kidney Diseases

Year:

2011

Language:

english

File:

PDF, 825 KB

english, 2011

23

Applications of statistics in clinical chemistry: A critical evaluation of regression lines

P.J.M. Wakkers, H.B.A. Hellendoorn, G.J.Op De Weegh, W. Heerspink

Journal:

Clinica Chimica Acta

Year:

1975

Language:

english

File:

PDF, 737 KB

english, 1975

24

Aspirin Is Beneficial in Hypertensive Patients With Chronic Kidney Disease: A Post-Hoc Subgroup Analysis of a Randomized Controlled Trial

Meg J. Jardine, Toshiharu Ninomiya, Vlado Perkovic, Alan Cass, Fiona Turnbull, Martin P. Gallagher, Sophia Zoungas, Hiddo J. Lambers Heerspink, John Chalmers, Alberto Zanchetti

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

25

Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention

Gansevoort, Ron T, Correa-Rotter, Ricardo, Hemmelgarn, Brenda R, Jafar, Tazeen H, Heerspink, Hiddo J Lambers, Mann, Johannes F, Matsushita, Kunihiro, Wen, Chi Pang

Journal:

Year:

2013

Language:

english

File:

PDF, 1.10 MB

english, 2013

26

Management of hyperkalaemia consequent to mineralocorticoid-receptor antagonist therapy

Roscioni, Sara S., de Zeeuw, Dick, Bakker, Stephan J. L., Lambers Heerspink, Hiddo J.

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2012

Language:

english

File:

PDF, 208 KB

english, 2012

27

Baseline characteristics in the Bardoxolone methyl EvAluation in patients with Chronic kidney disease and type 2 diabetes mellitus: the Occurrence of renal eveNts (BEACON) trial

Lambers Heerspink, H. J., Chertow, G. M., Akizawa, T., Audhya, P., Bakris, G. L., Goldsberry, A., Krauth, M., Linde, P., McMurray, J. J., Meyer, C. J., Parving, H.-H., Remuzzi, G., Christ-Schmidt, H.,

Journal:

Nephrology Dialysis Transplantation

Year:

2013

Language:

english

File:

PDF, 253 KB

english, 2013

28

Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): a randomised clinical trial

de Zeeuw, Dick, Anzalone, Deborah A, Cain, Valerie A, Cressman, Michael D, Heerspink, Hiddo J Lambers, Molitoris, Bruce A, Monyak, John T, Parving, Hans-Henrik, Remuzzi, Giuseppe, Sowers, James R, Vid

Journal:

The Lancet Diabetes & Endocrinology

Year:

2015

Language:

english

File:

PDF, 311 KB

english, 2015

29

Chevron Versus Mitchell Osteotomy in Hallux Valgus Surgery: A Comparative Study

Heerspink, F. O. Lambers, Verburg, H., Reininga, I.H.F., van Raaij, T.M.

Journal:

The Journal of Foot and Ankle Surgery

Year:

2015

Language:

english

File:

PDF, 235 KB

english, 2015

30

Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial

Slagman, M. C. J., Waanders, F., Hemmelder, M. H., Woittiez, A.-J., Janssen, W. M. T., Lambers Heerspink, H. J., Navis, G., Laverman, G. D.

Journal:

Year:

2011

Language:

english

File:

PDF, 113 KB

english, 2011

31

Intensive glucose control improves kidney outcomes in patients with type 2 diabetes

Perkovic, Vlado, Heerspink, Hiddo Lambers, Chalmers, John, Woodward, Mark, Jun, Min, Li, Qiang, MacMahon, Stephen, Cooper, Mark E, Hamet, Pavel, Marre, Michel, Mogensen, Carl Erik, Poulter, Neil, Manc

Journal:

Kidney International

Year:

2013

Language:

english

File:

PDF, 411 KB

english, 2013

32

Unmet need in diabetic nephropathy: failed drugs or trials?

de Zeeuw, Dick, Heerspink, Hiddo J L

Journal:

The Lancet Diabetes & Endocrinology

Year:

2016

Language:

english

File:

PDF, 127 KB

english, 2016

33

The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials

Czernichow, Sébastien, Zanchetti, Alberto, Turnbull, Fiona, Barzi, Federica, Ninomiya, Toshiaru, Kengne, André-Pascal, Lambers Heerspink, Hiddo J, Perkovic, Vlado, Huxley, Rachel, Arima, Hisatomi, Pat

Journal:

Journal of Hypertension

Year:

2011

Language:

english

File:

PDF, 761 KB

english, 2011

34

Dapagliflozin reduces albuminuria in patients with diabetes and hypertension receiving renin-angiotensin blockers

Heerspink, H. J. L., Johnsson, E., Gause-Nilsson, I., Cain, V. A., Sjöström, C. D.

Journal:

Diabetes, Obesity and Metabolism

Year:

2016

Language:

english

File:

PDF, 350 KB

english, 2016

35

Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes: Cardiovascular and Kidney Effects, Potential Mechanisms and Clinical Applications

Heerspink, Hiddo J.L., Perkins, Bruce A., Fitchett, David H., Husain, Mansoor, Cherney, David Z.I.

Journal:

Year:

2016

Language:

english

File:

PDF, 3.64 MB

english, 2016

36

Early renin-angiotensin system intervention is more beneficial than late intervention in delaying end-stage renal disease in patients with type 2 diabetes

Schievink, B., Kröpelin, T., Mulder, S., Parving, H.-H., Remuzzi, G., Dwyer, J., Vemer, P., de Zeeuw, D., Lambers Heerspink, H. J.

Journal:

Diabetes, Obesity and Metabolism

Year:

2016

Language:

english

File:

PDF, 573 KB

english, 2016

37

Effect of linagliptin on pulse wave velocity in early type 2 diabetes: A randomized, double-blind, controlled 26-week trial (RELEASE)

de Boer, Stefanie A., Heerspink, Hiddo J. L., Juárez Orozco, Luis E., van Roon, Arie M., Kamphuisen, Pieter W., Smit, Andries J., Slart, Riemer H. J. A., Lefrandt, Joop D., Mulder, Douwe J.

Journal:

Diabetes, Obesity and Metabolism

Year:

2017

Language:

english

File:

PDF, 293 KB

english, 2017

38

Renal trials in diabetes need a platform: time for a global approach?

de Zeeuw, Dick, Heerspink, Hiddo J L, Jardine, Meg, Perkovic, Vlado

Journal:

The Lancet Diabetes & Endocrinology

Year:

2017

Language:

english

File:

PDF, 136 KB

english, 2017

39

Reducing major risk factors for chronic kidney disease

Luyckx, Valerie A., Tuttle, Katherine R., Garcia-Garcia, Guillermo, Gharbi, Mohammed Benghanem, Heerspink, Hiddo J.L., Johnson, David W., Liu, Zhi-Hong, Massy, Ziad A., Moe, Orson, Nelson, Robert G.,

Journal:

Kidney International Supplements

Year:

2017

Language:

english

File:

PDF, 367 KB

english, 2017

40

Longitudinal Estimated GFR Trajectories in Patients With and Without Type 2 Diabetes and Nephropathy

Weldegiorgis, Misghina, de Zeeuw, Dick, Li, Liang, Parving, Hans-Henrik, Hou, Fan Fan, Remuzzi, Giuseppe, Greene, Tom, Heerspink, Hiddo J.L.

Journal:

American Journal of Kidney Diseases

Year:

2017

Language:

english

File:

PDF, 1.70 MB

english, 2017

41

Bardoxolone Methyl Improves Kidney Function in Patients with Chronic Kidney Disease Stage 4 and Type 2 Diabetes: Post-Hoc Analyses from Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes Study

Chin, Melanie P., Bakris, George L., Block, Geoffrey A., Chertow, Glenn M., Goldsberry, Angie, Inker, Lesley A., Heerspink, Hiddo J.L., O’Grady, Megan, Pergola, Pablo E., Wanner, Christoph, Warnock, D

Journal:

American Journal of Nephrology

Year:

2018

Language:

english

File:

PDF, 585 KB

english, 2018

42

Baseline characteristics and enrichment results of the Study Of diabetic Nephropathy with AtRasentan (SONAR) trial

Heerspink, Hiddo J.L., Andress, Dennis L., Bakris, George, Brennan, John J., Correa-Rotter, Ricardo, Hou, Fan Fan, Kitzman, Dalane W., Kohan, Donald, Makino, Hirofumi, McMurray, John, Perkovic, Vlado,

Journal:

Diabetes, Obesity and Metabolism

Year:

2018

Language:

english

File:

PDF, 788 KB

english, 2018

43

Effects of the sodium–glucose co-transporter 2 inhibitor dapagliflozin in patients with type 2 diabetes and Stages 3b–4 chronic kidney disease

Dekkers, Claire C J, Wheeler, David C, Sjöström, C David, Stefansson, Bergur V, Cain, Valerie, Heerspink, Hiddo J L

Journal:

Nephrology Dialysis Transplantation

Year:

2018

Language:

english

File:

PDF, 51 KB

english, 2018

44

Evaluation of renal and cardiovascular protection mechanisms of SGLT2 inhibitors: model-based analysis of clinical data

Hallow, Karen Melissa, Greasley, Peter J, Helmlinger, Gabriel, Chu, Lulu, Heerspink, Hiddo J.L., Boulton, David W

Journal:

American journal of physiology. Renal physiology

Year:

2018

Language:

english

File:

PDF, 1.97 MB

english, 2018

45

Albuminuria-lowering effect of dapagliflozin alone and in combination with saxagliptin and effect of dapagliflozin and saxagliptin on glycaemic control in patients with type 2 diabetes and chronic kidney disease (DELIGHT): a randomised, double-blind, placebo-controlled trial

Pollock, Carol, Stefánsson, Bergur, Reyner, Daniel, Rossing, Peter, Sjöström, C David, Wheeler, David C, Langkilde, Anna Maria, Heerspink, Hiddo J L

Journal:

The Lancet Diabetes & Endocrinology

Year:

2019

Language:

english

File:

PDF, 424 KB

english, 2019

46

Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy

Perkovic, Vlado, Jardine, Meg J., Neal, Bruce, Bompoint, Severine, Heerspink, Hiddo J.L., Charytan, David M., Edwards, Robert, Agarwal, Rajiv, Bakris, George, Bull, Scott, Cannon, Christopher P., Capu

Journal:

New England Journal of Medicine

Year:

2019

File:

PDF, 404 KB

2019

47

Effect of bardoxolone methyl on the urine albumin-to-creatinine ratio in patients with type 2 diabetes and stage 4 chronic kidney disease.

Rossing, Peter, Block, Geoffrey A., Chin, Melanie P., Goldsberry, Angie, Heerspink, Hiddo J.L., McCullough, Peter A., Meyer, Colin J., Packham, David, Pergola, Pablo E., Spinowitz, Bruce, Sprague, Stu

Journal:

Kidney International

Year:

2019

Language:

english

File:

PDF, 752 KB

english, 2019

48

Mixed‐effects models for slope‐based endpoints in clinical trials of chronic kidney disease

Vonesh, Edward, Tighiouart, Hocine, Ying, Jian, Heerspink, Hiddo L., Lewis, Julia, Staplin, Natalie, Inker, Lesley, Greene, Tom

Journal:

Statistics in Medicine

Year:

2019

Language:

english

File:

PDF, 1.89 MB

english, 2019

49

The incretin pathway as a therapeutic target in diabetic kidney disease: a clinical focus on GLP-1 receptor agonists

van Baar, Michaël J. B., van der Aart, Annemarie B., Hoogenberg, Klaas, Joles, Jaap A., Heerspink, Hiddo J. L., van Raalte, Daniël H.

Journal:

Therapeutic Advances in Endocrinology and Metabolism

Year:

2019

File:

PDF, 687 KB

2019

50

GFR Slope as a Surrogate End Point for Kidney Disease Progression in Clinical Trials: A Meta-Analysis of Treatment Effects of Randomized Controlled Trials

Inker, Lesley A., Heerspink, Hiddo J. L., Tighiouart, Hocine, Levey, Andrew S., Coresh, Josef, Gansevoort, Ron T., Simon, Andrew L., Ying, Jian, Beck, Gerald J., Wanner, Christoph, Floege, Jürgen, Li,

Journal:

Journal of the American Society of Nephrology

Year:

2019

Language:

english

File:

PDF, 712 KB

english, 2019